Mamaw isn’t amused. Three years after earning an Oscar nomination for playing JD Vance’s grandmother in the movie adaptation of his memoir, Hillbilly Elegy, Glenn Close has seemingly shaded Donald Trump’s running mate.

On Sunday, Close shared a smiling selfie featuring her cat, Eve, and wrote that the feline “would have left a bleeding mouse head in the bed of anyone who criticized any kind of lady with a CAT!” Her words appear to reference Vance’s recently resurfaced “childless cat ladies” remark, which he used to denigrate people who choose not to procreate.

The comment has earned harsh criticism from the likes of Jennifer Aniston (“I truly can’t believe this is coming from a potential VP of The United States,” she wrote in an Instagram story last month) and has since been defended by Vance’s wife, Usha, who told Fox News that people should focus less on the “three-word phrase” to understand that her husband actually meant “it can be really hard to be a parent in this country, and sometimes our policies are designed in a way that make it even harder.”

Until now, Close hasn’t publicly nodded toward Vance’s role as Trump’s vice presidential pick or her involvement in Hillbilly Elegy, which, since Vance joined the ticket, has been propelled back to the top of the best-seller list and Netflix’s list of most streamed titles. In the film, Close plays Mamaw, Vance’s grandmother, as she navigates a rocky relationship with her own daughter, Bev (Amy Adams), who is Vance’s mother. Close didn’t respond to Vanity Fair’s previous request for comment on Vance’s political rise, but told NME in 2021 that the movie “wasn’t made with politics in mind. [Director] Ron [Howard]’s intent—and I think he succeeded magnificently—is to tell the story of a very specific family.”

Perhaps signifying the film’s divisive nature is the fact that Close earned both Oscar and Razzie nominations for her supporting role in Hillbilly Elegy, losing to Minari’s Youn Yuh-jung and Music’s Maddie Ziegler, respectively.

During his victory speech after winning a US Senate seat in 2022, Vance thanked his real mamaw, Bonnie Blanton Vance, who died in 2005, and acknowledged their political differences. (Mamaw was a Democrat.) “You’re not always gonna agree with every vote that I take, [and] you’re not gonna agree with every single amendment that I offer in the United States Senate,” Vance said, “but I will never forget the woman who raised me.”